Caroline Sabin is Professor of Medical Statistics and Epidemiology at University College London (UCL). She has worked for many years on the analysis of large observational HIV databases with a particular interest in raising awareness of the biases inherent in these databases.
She is the principal investigator on the UK CHIC Study. Indeed, in 2000 she initiated the UK Collaborative HIV Cohort (UK CHIC) Study, a major multicentre study of more than 30,000 HIV-infected individuals in the UK. This study is one of the largest clinical cohorts of HIV-infected individuals worldwide.
Since 2001, she has been the principal statistician for the D:A:D (Data collection on Adverse events of anti-HIV Drugs) study, a large international multi-cohort study of more than 33,000 HIV-infected individuals which aims to describe the relationship between antiretroviral drugs and cardiovascular disease. She co-leads this project with collaborators in Copenhagen, provide advice on the strategic direction of the program of research, and liaise with the funding body (including representatives from the US Food and Drug Administration (FDA), the European Medicines Evaluation Agency (EMEA), the pharmaceutical industry and HIV patient community).
She has been closely involved with many other large HIV cohort studies and collaborations, both in the UK and abroad. She is a member of the Scientific Oversight Workpackage for the EuroCoord collaboration – this is a major collaborative effort that involves all cohorts of HIV-infected persons in Europe (with information on >250,000 infected individuals).